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Авторы проанализировали данные 326 участников американского исследования NHANES, у которых в 1999–2000 годах брали образцы крови. Концентрации PFNA и PFOSA обнаружились примерно у 95 процентов обследованных. Затем ученые оценили биологический возраст добровольцев. Выяснилось, что более высокий уровень PFNA в крови мужчин 50–64 лет был связан с более быстрым эпигенетическим старением по ряду показателей. У женщин такой связи обнаружено не было.